He arrived in Kolkata for higher studies. There, one of his relatives and childhood friend found him crying for the Lord in the midst of night. During these sleepless nights, one day he had a wonderful dream, in which the sage Narada appeared and uttered a mantra that would fetch him all perfection. However, he could not recall theh mantra in its entirety after waking up, which distressed him immeasurably. His detachment with the household life increased to an intolerable degree and he became determined to leave it behind. He went to get the permission of his widowed mother and thereafter proceeded towards Himalayas. High up in the Himalayan jungle, he fasted for three days from food and water, all the time calling out anxiously to the Lord. When he practically lost all awareness of the external world, he was given a divine order to seek out a spiritual master. He was also told that his guru would appear to him in the very place he had left. On reaching Sreedham Mayapur, he came accross a spiritual personality, towards whom he felt great attraction. On his return to Kolkata, he surrendered himself to the same personality, Om 108 Srila Bhaktisiddhanta Saraswati Thakur Prabhupada on September 4, 1927. His initiated name was 'Sree Hayagriva Das Brahmachari'. Seeing his indomitable spirit of service, Srila Prabhupada used to call him source of 'Volcanic Energy'. After the disappearance of Thakur Prabhupada in 1936, he took sannyas in Phalguni Purnima in 1944 in Jagannath Puri on the request of his godbrothers. His sannyas name was Parivrajaka acharya Tridandi Swami 108 Sree Sremad Bhakti Dayita Madhav Goswami Maharaj. In a short period of 29 years, he established more than 20 maths all over India. His teachings are still helping thousands of people to progress on social, moral, and spiritual paths. He was serving the Supreme Lord 24 hours a day. He had a most ideal character.
Before his disappearance in 1979, he appointed his dearmost disciple, His Divine Grace Srila Bhakti Ballabh Tirtha Goswami Maharaj as his successor.
Since then he has been engaged incessantly in the service of the Lord and the Vaishnavas following the footsteps of his gurudev. Responding to the repeated requests by foreign devotees, Srila Acharyadev gave his approval to the establishment of Gokul (Global Organization of Krishnachaitanya's Universal Love) in 1997. He is also serving as the President of the World Vaishnava Association (WVA). For the last five decades, Srila Acharyadev has been engaged in preaching the gospel of Sree Chaitanya Mahaprabhu's Universal Divine Love.